VIPSolutions logo ✨ VIPSolutions

Downstream Filtration After each production-scale fermentation batch, the entire filtration operation for this batch must be completed within 20 hours. Each filter press operates on a 2- hour cycle time. The ratio of wet filter residue to feed liquid volume is known to be 30%. The filling coefficient inside the filter frame is taken as 0.8. Determine the appropriate number of plate-and-frame filter presses required. Use the model BAS20/635-25, with a total internal frame volume V =260 L. Give step-by-step solution with explanation and final answer:Pilot Parameter Unit Tank dameteradd Lm Tank height (H) 2 m Loading factor 64 % Impeller diameter (d) 0.5 m Agitation speed 300 pm Fermentation time 180 h tion t ms : Gauge pressure of tank 0.3 MPa Temperature in tank 28 °C Aeration rate 12 VVM (standard conditions) Broth viscosity 0.1 Pas Broth density 1050 kg/m? Final lipase concentration in broth ~~ 18.18 g/L

Question:

Downstream Filtration After each production-scale fermentation batch, the entire filtration operation for this batch must be completed within 20 hours. Each filter press operates on a 2- hour cycle time. The ratio of wet filter residue to feed liquid volume is known to be 30%. The filling coefficient inside the filter frame is taken as 0.8. Determine the appropriate number of plate-and-frame filter presses required. Use the model BAS20/635-25, with a total internal frame volume V =260 L. Give step-by-step solution with explanation and final answer:Uploaded ImagePilot Parameter Unit Tank dameteradd Lm Tank height (H) 2 m Loading factor 64 % Impeller diameter (d) 0.5 m Agitation speed 300 pm Fermentation time 180 h tion t ms : Gauge pressure of tank 0.3 MPa Temperature in tank 28 °C Aeration rate 12 VVM (standard conditions) Broth viscosity 0.1 Pas Broth density 1050 kg/m? Final lipase concentration in broth ~~ 18.18 g/L

This is AI generated Response.
Asked by: singaluri krishna kumari
Created at: 2025-12-18 01:54:12

Final Answer:

Rendered Raw Text
Did you like this answer?
# Step-by-Step Solution: Filter Press Sizing for Downstream Filtration Let's break down the information and solve for the required number of filter presses. --- ## **Step 1: Calculate Fermentation Broth Volume** - **Tank diameter (D):** 1 m - **Tank height (H):** 2 m - **Loading factor:** 64% ### **Calculate the total tank volume:** \[ V_{\text{tank}} = \pi \left(\frac{D}{2}\right)^2 H = \pi (.5)^2 \times 2 = \pi \times .25 \times 2 \approx 1.57\, \text{m}^3 \] ### **Actual broth volume:** \[ V_{\text{broth}} = \text{Loading factor} \times V_{\text{tank}} = .64 \times 1.57 \approx 1.01\, \text{m}^3 = 101\, \text{L} \] --- ## **Step 2: Wet Filter Residue and Feed Volume** - **Wet filter residue to feed volume ratio = 30%** So, for every 1 L of feed, .3 L becomes wet residue. \[ V_{\text{residue}} = .3 \times V_{\text{broth}} = .3 \times 101 = 303\, \text{L} \] --- ## **Step 3: Filter Frame Filling Coefficient** - **Filling coefficient = .8** - **Total filter press frame volume (V):** 260 L (per press) Effective volume per cycle per press: \[ V_{\text{press, effective}} = .8 \times 260 = 208\, \text{L} \] --- ## **Step 4: Number of Filter Cycles Needed** Each press can handle 208 L of residue per cycle. \[ \text{Cycles required} = \frac{V_{\text{residue}}}{V_{\text{press, effective}}} = \frac{303}{208} \approx 1.46 \] But this is for one press and one batch's residue. --- ## **Step 5: Time Constraints** - **Total operation time allowed:** 20 hours - **Each filter press cycle time:** 2 hours Maximum number of cycles a single press can run in 20 hours: \[ \text{Cycles per press} = \frac{20}{2} = 10 \] --- ## **Step 6: Number of Presses Needed** Each press can process 208 L of residue per cycle, and can run 10 cycles in 20 hours: \[ \text{Total residue processed per press in 20 h} = 10 \times 208 = 208\, \text{L} \] But we only need to process 303 L of residue per batch (from the 101 L broth). \[ \text{Number of presses needed} = \frac{V_{\text{residue}}}{\text{Residue processed per press in 20 h}} = \frac{303}{208} \approx .146 \] Since you can't have a fraction of a filter press, **you only need 1 filter press** (since one press can handle much more than 303 L in 20 hours). --- ## **Final Answer** ### **Only 1 plate-and-frame filter press (BAS20/635-25) is required to filter one batch in 20 hours.** --- ### **Summary Table** | Parameter | Value | |---------------------------------|------------------| | Broth volume per batch | 101 L | | Wet filter residue per batch | 303 L | | Effective volume per press/cycle| 208 L | | Cycles per press in 20 h | 10 | | Residue handled per press/20 h | 208 L | | Number of presses needed | 1 | --- **If you have multiple fermenters or simultaneous batches, scale accordingly.**

📢 Instructions:

  • Ask anything relatd to above question only.
  • For new Question goto :

Study Help, Fast Answers

VIPSolutions focuses on clear, step‑by‑step explanations so you can learn quickly. Whether you need an AI‑generated walkthrough or a short hint to get unstuck, each solution is organized for fast reading and easy review later.

Search similar questions, compare approaches, and bookmark the best answers for revision. Our goal is simple: quick, reliable study help that feels natural—not noisy.